Researchers from the Georgia Institute of Technology have developed ways to manufacture solid and hollow metal, silicon, plastic and glass microneedles that range in size from one millimeter to one thousandth of a millimeter.
The researchers demonstrated that an array of 400 microneedles can be used to pierce human skin, and successfully used a similar micro array to deliver insulin to diabetic rats.
Solid microneedles could eventually be used with drug patches to increase diffusion rates; hollow needles could eventually be used with drug patches and timed pumps to deliver drugs at specific times, according to the researchers.
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